British Air Force Typhoon FGR4s have operated alongside French aircraft in a joint strike on an subterranean weapons facility in Syria employed by the IS group, as stated by the British defence ministry.
The site, pinpointed through surveillance, was believed to be containing munitions and bombs, the announcement noted, and was located in hills just above Palmyra in the heart of Syria.
"Our fighter planes employed laser-guided Paveway IV weapons to target a series of access tunnels providing entry to the site... early reports are that the objective was successfully hit," the MoD said.
There was no sign of any harm to civilians in the strike conducted Saturday night and all the aircraft returned to base without incident, the ministry further stated.
The British jets were backed up by a Voyager aerial refuelling aircraft.
IS - also known as ISIS - enforced militant control over large swathes of Iraq and Syria prior to its 2019 collapse.
"This strike demonstrates British leadership, and determination to stand shoulder to shoulder with allied nations, to eliminate any revival of IS and their dangerous and violent ideologies in the Middle East," Britain's Defence Chief the Defence Secretary stated.
British military aircraft have carried out patrols over Syria to "deter any attempted resurgence" of IS subsequent to its routing at the climactic battle in Baghuz in 2019, the ministry said.
"I must thank all the members of the UK armed forces participating in this mission for their professionalism and their bravery," the Defence Secretary commented. "They were part of numerous UK service members stationed over the holidays. This action, to remove dangerous terrorists who pose a risk to our way of life, highlights how British military are ready to step up, all year round, protecting the UK at home and strong abroad."
Last December, the US military carried out what it called a "massive strike" targeting Daesh sites in the country, following an assault claimed the lives of two US troops and a civilian interpreter in Palmyra.
The United Nations says Daesh still maintains an estimated 5,000 to 7,000 militants in Syria and Iraq.